Antiepileptic drugs: changing between different manufacturers’ products

You download the guidance from the MHRA – Antiepileptic Drugs

Summary and key messages
 Depending on which antiepileptic drug you take, your doctor and pharmacist may recommend that the
medicine you receive is always made by the same manufacturer. This is because for some antiepileptic
drugs, there is a chance that switching to a different manufacturer could cause loss of seizure control, or
could result in side effects.
 For many antiepileptic drugs however, it is quite safe to switch between different manufacturers of a
particular drug.
 In order to help doctors decide whether their patients should stick with the same manufacturer’s
product or whether it is safe to switch to different products, antiepileptic drugs have now been put into
three groups.
 Your doctor will consider your own particular circumstances and the drug that you’re taking before
deciding whether to recommend that you stick with the same manufacturer’s product or not.

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